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KMID : 1033620140410010009
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Clinical and Experimental Reproductive Medicine
2014 Volume.41 No. 1 p.9 ~ p.14
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Comparison between intracytoplasmic sperm injection and intracytoplasmic morphologically selected sperm injection in oligo-astheno-teratozoospermia patients
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Kim Hyung-Jun
Yoon Hye-Jin
Jang Jung-Mi
Oh Hwa-Soon
Lee Yong-Jun
Lee Won-Don
Yoon San-Hyun
Lim Jin-Ho
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Abstract
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Objective: The aim of this study was to evaluate the efficiency of the intracytoplasmic morphologically selected sperm injection (IMSI) technique compared with conventional ICSI and previous ICSI attempts in oligo-astheno-teratozoospermia (OAT) patients.
Methods: The sperms were selected under high magnification (6,600×) and used to induce fertilization in previous ICSI patients by IMSI. These results were compared with previous conventional ICSI cycles in patients with OAT infertility.
Results: These results demonstrated no significant difference in the fertilization rate between IMSI and previous ICSI cycles (67.7% vs. 65.0%). However, the pregnancy and implantation rates with IMSI were significantly higher than those of the ICSI cycles (33.3% vs. 12.5% and 14.6% vs. 5.4%, respectively; p<0.05). The miscarriage rate among pregnant patients (18.2% vs. 37.5%) showed no statistically significant difference between groups.
Conclusion: Compared to conventional ICSI, this study found that IMSI increased the IVF-ET success rates in patients with OAT.
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KEYWORD
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High magnification, Intracytoplasmic sperm injection, Intracytoplasmic morphologically selected sperm injection, Oligo-astheno-teratozoospermia
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